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KMID : 0377519870120030409
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Chung-Ang Journal of Medicine
1987 Volume.12 No. 3 p.409 ~ p.419
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A Study on the Human Lung Development
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Kim, Young-Kun/김영건
Kim, Ho-dirk/Rah, Bong-jin/김호덕/라봉진
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Abstract
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To investigate the developmental morphology of the human fetal lung, lung tissues taken from the periphery of the right lower lobes of 31 stillborn Korean fetuses of both sexes were studied.
The fetal period proper of the human lung development could be subdivided into three continucus stages, i.e., an early stage of the formation of conductive airways(pseudoglandular, before 16 weeks of gestation), a middle stage of the ´development of lung parenchyme (canalicular, between 17 and 28 weeks of gestation), and a late stage of transition to vascular: crgan (terminal sac, between 27 to 28 and 36 weeks of gestation; and alveolar, end
of this stage). The prenatal alveolar phase could be identified by the end of the ninth month of intrauterine life.
The elastic fibers appeared in the pleura; in the well of accompanying artery of the bronchiole, and in the subepithelial tissue at a late of the pseudoglandular stage. By 24 weeks of gestation the elastic fibers were present closely contact with the airspaces. Blood capillaries were observed closely related to the airspaces by the late canalicular or by the early terminal sac stage. Further vascularization and further development of the elastic fiber system were noted during the terminal sac stage.
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